/* Index - Start -----------------------------------
1. Custom Fonts

2. Global css 
/* Custom Fonts - Start ----------------------------------- */
@import url("https://maxcdn.bootstrapcdn.com/font-awesome/4.7.0/css/font-awesome.min.css");

@font-face {
    font-family: "Helvetica55Roman";
    src: url("../fonts/Helvetica-Neue-LT-Com-55-Roman.ttf") format("truetype");
    font-style: normal;
    font-weight: normal;
    text-rendering: optimizeLegibility;
}

@font-face {
    font-family: "Helvetica65Medium";
    src: url("../fonts/Helvetica-Neue-LT-Com-65-Medium.ttf") format("truetype");
    font-style: normal;
    font-weight: normal;
    text-rendering: optimizeLegibility;
}

@font-face {
    font-family: "Helvetica75Bold";
    src: url("../fonts/Helvetica-Neue-LT-Com-75-Bold.ttf") format("truetype");
    font-style: normal;
    font-weight: normal;
    text-rendering: optimizeLegibility;
}

@font-face {
    font-family: "Helvetica85Heavy";
    src: url("../fonts/Helvetica-Neue-LT-Com-85-Heavy.ttf") format("truetype");
    font-style: normal;
    font-weight: normal;
    text-rendering: optimizeLegibility;
}

@font-face {
    font-family: 'HelveticaNeue-Medium';
    src: url("../fonts/HelveticaNeue-Medium.eot?#iefix") format("embedded-opentype"), url("../fonts/HelveticaNeue-Medium.woff2") format("woff2"), url("../fonts/HelveticaNeue-Medium.woff") format("woff"), url("../fonts/HelveticaNeue-Medium.ttf") format("truetype"), url("../fonts/HelveticaNeue-Medium.otf") format("otf");
    font-style: normal;
    font-weight: normal;
    text-rendering: optimizeLegibility;
}

@font-face {
    font-family: "HelveticaNeueBold";
    src: url("../fonts/HelveticaNeue-Bold.eot?#iefix") format("embedded-opentype"), url("../fonts/HelveticaNeue-Bold.woff2") format("woff2"), url("../fonts/HelveticaNeue-Bold.woff") format("woff"), url("../fonts/HelveticaNeue-Bold.ttf") format("truetype"), url("../fonts/HelveticaNeue-Bold.otf") format("otf");
    font-style: normal;
    font-weight: normal;
    text-rendering: optimizeLegibility;
}

@font-face {
    font-family: "HelveticaHeavy";
    src: url("../fonts/HelveticaNeueHeavy.eot?#iefix") format("embedded-opentype"), url("../fonts/HelveticaNeueHeavy.woff2") format("woff2"), url("../fonts/HelveticaNeueHeavy.woff") format("woff"), url("../fonts/HelveticaNeueHeavy.ttf") format("truetype"), url("../fonts/HelveticaNeueHeavy.otf") format("otf");
    font-style: normal;
    font-weight: normal;
    text-rendering: optimizeLegibility;
}

@font-face {
    font-family: "HelveticaNeue";
    src: url("../fonts/HelveticaNeue.eot?#iefix") format("embedded-opentype"), url("../fonts/HelveticaNeue.woff") format("woff"), url("../fonts/HelveticaNeue.woff2") format("woff2"), url("../fonts/HelveticaNeue.otf") format("otf"), url("../fonts/HelveticaNeue.ttf") format("truetype");
    font-style: normal;
    font-weight: normal;
    text-rendering: optimizeLegibility;
}

@font-face {
    font-family: "HelveticaNeueLight";
    src: url("../fonts/HelveticaNeueLight.eot?iefix") format("embedded-opentype"), url("../fonts/HelveticaNeueLight.ttf") format("truetype"), url("../fonts/HelveticaNeueLight.otf") format("otf"), url("../fonts/HelveticaNeueLight.woff2") format("woff2"), url("../fonts/HelveticaNeueLight.woff") format("woff");
    font-style: normal;
    font-weight: normal;
    text-rendering: optimizeLegibility;
}

@font-face {
    font-family: "HelveticaLight";
    src: url("../fonts/HelveticaLT45Light.ttf") format("truetype"), url("../fonts/HelveticaLT45Light.eot?iefix") format("embedded-opentype"), url("../fonts/HelveticaLT45Light.otf") format("otf"), url("../fonts/HelveticaLT45Light.woff") format("woff"), url("../fonts/HelveticaLT45Light.woff2") format("woff2");
    font-style: normal;
    font-weight: normal;
    text-rendering: optimizeLegibility;
}

@font-face {
    font-family: "HelveticaNeueLTStd-Hv";
    src: url("../fonts/Helvetica-Neue-LT-Std-85-Heavy.ttf") format("truetype"), url("../fonts/Helvetica-Neue-LT-Std-85-Heavy.eot?iefix") format("embedded-opentype"), url("../fonts/Helvetica-Neue-LT-Std-85-Heavy.otf") format("otf"), url("../fonts/Helvetica-Neue-LT-Std-85-Heavy.woff") format("woff"), url("../fonts/Helvetica-Neue-LT-Std-85-Heavy.woff2") format("woff2");
    font-style: normal;
    font-weight: normal;
    text-rendering: optimizeLegibility;
}

@font-face {
    font-family: "HelveticaNeueLTStd-Bd";
    src: url("../fonts/HelveticaNeueLTStd-Bd.ttf") format("truetype"), url("../fonts/HelveticaNeueLTStd-Bd.eot?iefix") format("embedded-opentype"), url("../fonts/HelveticaNeueLTStd-Bd.otf") format("otf"), url("../fonts/HelveticaNeueLTStd-Bd.woff") format("woff"), url("../fonts/HelveticaNeueLTStd-Bd.woff2") format("woff2");
    font-style: normal;
    font-weight: normal;
    text-rendering: optimizeLegibility;
}

@font-face {
    font-family: "HelveticaNeueLTStd-Roman";
    src: url("../fonts/HelveticaNeue-Roman.ttf") format("truetype"), url("../fonts/HelveticaNeue-Roman.eot?iefix") format("embedded-opentype"), url("../fonts/HelveticaNeue-Roman.otf") format("otf"), url("../fonts/HelveticaNeue-Roman.woff") format("woff"), url("../fonts/HelveticaNeue-Roman.woff2") format("woff2");
    font-style: normal;
    font-weight: normal;
    text-rendering: optimizeLegibility;
}

@font-face {
    font-family: "HelveticaNeueItalic";
    src: url("../fonts/HelveticaNeueItalic.ttf") format("truetype"), url("../fonts/HelveticaNeueItalic.eot?iefix") format("embedded-opentype"), url("../fonts/HelveticaNeue-Italic.otf") format("otf"), url("../fonts/HelveticaNeue-Italic.woff") format("woff"), url("../fonts/HelveticaNeueItalic.woff2") format("woff2");
    font-style: normal;
    font-weight: normal;
    text-rendering: optimizeLegibility;
}

@font-face {
    font-family: "HelveticaNeueItalicBold";
    src: url("../fonts/HelveticaNeueBoldItalic.ttf") format("truetype");
    font-style: normal;
    font-weight: normal;
    text-rendering: optimizeLegibility;
}

@font-face {
    font-family: "CenturyGothicBold";
    src: url("../fonts/CenturyGothicBold.ttf") format("truetype");
    font-style: normal;
    font-weight: normal;
    text-rendering: optimizeLegibility;
}

@font-face {
    font-family: "CenturyGothic";
    src: url("../fonts/CenturyGothic.ttf") format("truetype");
    font-style: normal;
    font-weight: normal;
    text-rendering: optimizeLegibility;
}


@font-face {
    font-family: "OpenSans-Regular";
    src: url("../fonts/OpenSans-Regular.ttf") format("truetype");
    font-style: normal;
    font-weight: normal;
    text-rendering: optimizeLegibility;
}

@font-face {
    font-family: "OpenSans-Light";
    src: url("../fonts/OpenSans-Light.ttf") format("truetype");
    font-style: normal;
    font-weight: normal;
    text-rendering: optimizeLegibility;
}

@font-face {
    font-family: "OpenSans-LightItalic";
    src: url("../fonts/OpenSans-LightItalic.ttf") format("truetype");
    font-style: normal;
    font-weight: normal;
    text-rendering: optimizeLegibility;
}

@font-face {
    font-family: "OpenSans-Bold";
    src: url("../fonts/OpenSans-Bold.ttf") format("truetype");
    font-style: normal;
    font-weight: normal;
    text-rendering: optimizeLegibility;
}

@font-face {
    font-family: "OpenSans-BoldItalic";
    src: url("../fonts/OpenSans-BoldItalic.ttf") format("truetype");
    font-style: normal;
    font-weight: normal;
    text-rendering: optimizeLegibility;
}

@font-face {
    font-family: "OpenSans-ExtraBold";
    src: url("../fonts/OpenSans-ExtraBold.ttf") format("truetype");
    font-style: normal;
    font-weight: normal;
    text-rendering: optimizeLegibility;
}

@font-face {
    font-family: "OpenSans-ExtraBoldItalic";
    src: url("../fonts/OpenSans-ExtraBoldItalic.ttf") format("truetype");
    font-style: normal;
    font-weight: normal;
    text-rendering: optimizeLegibility;
}

@font-face {
    font-family: "OpenSans-SemiBold";
    src: url("../fonts/OpenSans-SemiBold.ttf") format("truetype");
    font-style: normal;
    font-weight: normal;
    text-rendering: optimizeLegibility;
}

@font-face {
    font-family: "OpenSans-SemiboldItalic";
    src: url("../fonts/OpenSans-SemiboldItalic.ttf") format("truetype");
    font-style: normal;
    font-weight: normal;
    text-rendering: optimizeLegibility;
}

@font-face {
    font-family: "OpenSans-Italic";
    src: url("../fonts/OpenSans-Italic.ttf") format("truetype");
    font-style: normal;
    font-weight: normal;
    text-rendering: optimizeLegibility;
}

@font-face {
    font-family: "OpenSans-BoldItalic";
    src: url("../fonts/OpenSans-BoldItalic.ttf") format("truetype");
    font-style: normal;
    font-weight: normal;
    text-rendering: optimizeLegibility;
}

@font-face {
    font-family: "OpenSans-CondBold";
    src: url("../fonts/OpenSans-CondBold.ttf") format("truetype");
    font-style: normal;
    font-weight: normal;
    text-rendering: optimizeLegibility;
}

@font-face {
    font-family: "OpenSans-CondLight";
    src: url("../fonts/OpenSans-CondLight.ttf") format("truetype");
    font-style: normal;
    font-weight: normal;
    text-rendering: optimizeLegibility;
}

@font-face {
    font-family: "OpenSans-CondLightItalic";
    src: url("../fonts/OpenSans-CondLightItalic.ttf") format("truetype");
    font-style: normal;
    font-weight: normal;
    text-rendering: optimizeLegibility;
}

/* ------------------------------------- Custom Fonts - End */

/* Global css - Start ----------------------------------- */
body {
    color: #353c42;
    font-family: "OpenSans-Regular";
    line-height: 26px;
    font-size: 18px;
    overflow-x: hidden;
}

html {
    scroll-behavior: smooth;
}

/*----common css starts------*/
li {
    list-style: none;
}

.mobileViewOnly {
    display: none;
}

.desktopViewOnly {
    display: block;
}

.HelveticaHeavy {
    font-family: "OpenSans-ExtraBold" !important;
}

.helveticaNeueBold {
    font-family: "OpenSans-Bold" !important;
}

.HelveticaNeue,
.helvetica-regular {
    font-family: "OpenSans-Regular" !important;
    font-weight: 400;
}

.helveticaItalic {
    font-family: "OpenSans-Italic" !important;
}

.helveticaItalicbold,
.openSansItalicbold {
    font-family: "OpenSans-BoldItalic" !important;
}

.openSansItalic {
    font-family: "OpenSans-Italic" !important;
}

.CenturyGothicBold {
    font-family: "CenturyGothicBold";
}

.CenturyGothic {
    font-family: "CenturyGothic";
}

.HelveticaNeueFont {
    font-family: "HelveticaNeue" !important;
}

.helveticaMedium {
    font-family: "OpenSans-SemiBold";
}

.grey-text p span.helveticaNeueBold {
    font-family: "OpenSans-Bold" !important;
}

.orange {
    color: #ea721f !important;
}

.red-color {
    color: #ff0000 !important;
}

.blackberry {
    color: #24005b !important;
}

.blackColorBg {
    color: #000000 !important;
}

.blackcolor {
    color: #000 !important;
}

.greytext {
    color: #59595b !important;
}

.blacktext {
    color: #59595b !important;
}

.MBminus {
    margin-top: -20px !important;
    float: left;
}

sup {
    font-size: 65%;
}

.pink {
    color: #ff00ff;
}

b,
strong {
    font-family: "OpenSans-Bold";
    font-weight: bold;
}

a {
    color: inherit;
}

a.underline-text:hover {
    color: inherit;
    text-decoration: underline;
}

.privacy-text a.underline-text:hover {
    color: #353c42;
    text-decoration: underline;
}


.helveticaLight {
    font-family: "OpenSans-Light" !important;
}

.helveticaBold {
    font-family: "OpenSans-Bold" !important;
}

.helvetica75Bold {
    font-family: "OpenSans-Bold" !important;
}

.Helvetica65Medium {
    font-family: "OpenSans-SemiBold" !important;
}

.Helvetica85Heavy {
    font-family: "OpenSans-ExtraBold" !important;
}




/*----common css ends------*/
/*----header starts------*/

.content-wrapper {
    width: 100%;
    overflow: hidden;
}

.logo-inner {
    position: relative;
    top: 15px;
    z-index: 1024;
}

.gastric-hcp .top-header {
    position: relative;
    padding-right: 0;
    background: #f4f4f4;
    z-index: 9;
}

.gastric-hcp .top-header-text {
    top: 0 !important;
    position: relative;
    left: 40px;
}



.top-header .top-header-links {
    float: right;
    padding-top: 13px;
    padding-right: 0;
    padding-left: 0;
}

li.dropdown.cancerTypeDropdown ul.dropdown-menu.show {
    padding: 8px 8px;
    left: -15px !important;
    width: 305px;
}



.bottom-header .enhertu-nsclc-hcp-navigation li:nth-child(2) a {
    padding: 10px 0px 10px 0px;
}

li.dropdown.cancerTypeDropdown li:last-child {
    margin-bottom: 0;
}

.enhertu-nsclc-hcp-navigation ul {
    width: 100%;
    display: flex;
    margin-left: 0px;
    padding: 10px 0 0 0;
    margin-bottom: 0;
}

li.dropdown.cancerTypeDropdown a.dropdown-toggle b {
    position: relative;
    left: 5px;
    top: 5px;
}

.top-header {
    float: left;
    width: 100%;
    padding: 5px 0px 6px;
}



.top-header .top-header-links .patient-info-link b {
    display: none;
}

.top-header .top-header-links li a {
    text-decoration: none;
    font-size: 14px;
    color: #353c42;
    padding: 0 0px;
    font-family: "OpenSans-Regular";
    display: flex;
    text-align: center;
    margin: 0 15px;
    line-height: 22px;
}

li.dropdown.cancerTypeDropdown {
    background: #f8f8f9;
    padding: 5px 3px;
    border-radius: 3px;
}

.top-header .top-header-links li.nurse-corner-link li:nth-child(3) a {
    margin-left: 15px;
}

/*.top-header .top-header-links li:last-child a,
.top-header .top-header-links li:nth-child(3) a,
.top-header .top-header-links li:nth-child(4) a {
    border-right: 0px;
    background: url(../images/mNSCLC/black-arrow.png) no-repeat right transparent;
}
*/
.top-header .top-header-links li:last-child a,
.top-header .top-header-links li.prescribing-info a,
.top-header .top-header-links li.medication-guide a {
    border-right: 0px;
    position: relative;
}

.top-header .top-header-links li.prescribing-info a::after {
    content: "";
    position: absolute;
    right: -12px;
    background: url(../images/mNSCLC/black-arrow.svg) no-repeat right transparent;
    top: 2px;
    width: 18px;
    height: 19px;
}

.top-header .top-header-links li:last-child a::after,
.top-header .top-header-links li.medication-guide a::after {
    content: "";
    position: absolute;
    right: -5px;
    background: url(../images/mNSCLC/black-arrow.svg) no-repeat right transparent;
    top: 2px;
    width: 18px;
    height: 19px;
}

li.dropdown.cancerTypeDropdown li.active a::after {
    display: none;
}

a.gastric-hcp-site-link span.HelveticaNeue {
    font-size: 16px !important;
    color: #260859;
}

.tableChart ul.listBlock2 li {
    position: relative;
    padding-left: 15px;
    text-align: left;
    line-height: 22px;
    color: #59595b;
}

.pink {
    color: #eb008b;
}

.BtmButtonDiv.row.justify-content-center.mb-3.destinybutton {
    margin: 54px 0 0 0;
    float: left;
    width: 100%;
}

.sign-up-wrapper .form-control,
.contactRepForm .form-control {
    border: 1px solid #586475;
    border-radius: 0px;
    height: calc(1.3em + 0.75rem + 0px);
    width: 402px;
    height: 32px;
}

#signup-form .form-control {
    line-height: 21px;
}

.sign-up-wrapper select.form-control {
    background-position: right;
}

.pagenotfound-wrapper.innercontentWrapper .BtmButtonDiv a.button-link {
    font-size: 18px;
    line-height: 38px;
    /* width: 100%; */
    /* padding: 18px 10px 18px 10px; */
    width: 265px;
    height: 55px;
    line-height: 16px;
}

.siteMap .sitemap-list li {
    position: relative;
    padding-left: 15px;
    margin-bottom: 5px;
}

.dosing-administration .card-grn1 a.button-link {
    padding: 15px;
    width: 100%;
}

.dosing-administration a.button-link {
    padding: 10px 0;
    width: 326px;
    line-height: 21px;
    font-family: "OpenSans-Bold";
}

/*.mechanism-action .mTop30 img,.efficacy-data .chartsImages img{width: 100%;}*/
.top-header .top-header-links .rightLinks {
    float: right;
    padding-top: 8px;
}

.review a {
    color: #2e1b46;
}

.review {
    font-size: 14px;
    position: relative;
    left: 0px;
    top: 0px;
    font-family: "OpenSans-Bold";
}



.top-header .top-header-links .gastric-hcp-site-link {
    margin-top: 8px;
    font-size: 12px;
    color: #260859;
    text-transform: uppercase;
    padding-right: 0px;
    font-family: "OpenSans-Bold";
    float: right;
    width: 88px;
    margin-right: 5px;
    text-decoration: none;
    line-height: 12px;
    background: url(../images/mNSCLC/black-arrow.svg) no-repeat right transparent;
    background-size: 10%;
}

.top-header .top-header-links li a.nurse-link {
    font-size: 12px;
    font-family: "OpenSans-ExtraBold";
    text-transform: uppercase;
    width: 80px;
    margin-right: 10px;
    text-decoration: underline;
    white-space: normal;
}

.top-header .top-header-links li a.nurse-link .fa {
    font-weight: 700;
    top: 10px;
    position: relative;
    font-size: 16px;
}

.top-header .top-header-links.desktopViewOnly li#nurseCornerLinks b {
    position: absolute;
    right: 10px;
    top: 15px;
    bottom: 0;
    height: 11px;
    display: block;
    margin: auto;
}

.top-header .top-header-links li a.nurse-link .fa:before {
    content: "\f107" !important;
}

.top-header .top-header-links li.show .fa:before,
.top-header .top-header-links li.show a.nurse-link .fa:before {
    content: "\f106" !important;
}

.top-header .top-header-links li#nurseCornerLinks ul {
    margin: 0px 0 0;
    top: 42px !important;
    right: auto;
    transform: none !important;
    left: auto !important;
    width: 220px;
    padding: 0px 0px;
    box-shadow: 0 3px 6px 0 rgb(0 0 0 / 16%);
    background-color: #f4f4f4;
    margin: 0.025rem 0 0;
    border-radius: 0 !important;
    border: 0;
    margin-left: 15px;
}

.top-header .top-header-links li#nurseCornerLinks .dropdown-menu li {
    padding: 10px 0px;
}

.top-header .top-header-links li#nurseCornerLinks ul.dropdown-menu li a {
    font-family: "OpenSans-Regular";
    font-size: 14px;
    font-weight: normal;
    text-align: left;
    color: #2e1a46;
    text-transform: none;
    width: 100%;
    text-align: left;
    text-decoration: underline;
}

span.enhertuText {
    border-bottom: #260859 1px solid;
}

span.whiteText {
    color: #260859;
    border-bottom: #260859 1px solid;
}

.bottom-header {
    position: relative;
    margin-top: 0px;
    z-index: 8;
}

.pink-text {
    color: #eb008b;
    font-size: 24px;
    text-shadow: none;
    padding-right: 43px;
}

.pink-color {
    color: #eb008b;
}

li.innerLogo img {
    width: auto;
    height: 55px;
}

.bottom-header .enhertu-nsclc-hcp-navigation li.innerLogo {
    width: 167px;
}

li.innerLogo img {
    width: 100%;
    height: auto;
}

p.paragraph {
    color: #59595B;
    font-size: 12px;
    font-family: "OpenSans-Regular";
}

.enhertu-nsclc-hcp-navigation {
    /* width: 100%; 
    float: right; */
    padding-bottom: 0;
    padding-top: 0;
    padding-left: 0;
    padding-right: 0;
    float: left;
}

.bottom-header .enhertu-nsclc-hcp-navigation li.dropdown .dropdown-menu li {
    padding: 0;
}

.bottom-header .enhertu-nsclc-hcp-navigation li:first-child {
    margin-left: 0;
}

.bottom-header .enhertu-nsclc-hcp-navigation li {
    flex: auto;
    margin-right: 0px;
    position: relative;
    width: auto;
    height: 40px;
    margin-left: 34px;
}


.bottom-header .enhertu-nsclc-hcp-navigation li .dropdown-menu li {
    height: auto;
    background-color: #f8f8f9;
    border-bottom: 1px solid #c3c7cb;
    margin-left: 0;
}

.bottom-header .enhertu-nsclc-hcp-navigation li:nth-child(3) .dropdown-menu li:nth-child(2) a,
.bottom-header .enhertu-nsclc-hcp-navigation li:nth-child(2) .dropdown-menu li:nth-child(2) a {
    padding-right: 35px;
}

.bottom-header .enhertu-nsclc-hcp-navigation .nav .open>a,
.bottom-header .enhertu-nsclc-hcp-navigation .nav .open>a:focus,
.bottom-header .enhertu-nsclc-hcp-navigation .nav .open>a:hover {
    background: none;
}

/*.bottom-header .enhertu-nsclc-hcp-navigation ul li:first-child {
    display: none;
}*/
div#bs-example-navbar-collapse-1 {
    position: relative;
}

#bs-example-navbar-collapse-1 {
    border-bottom: 1px solid #260859;
    padding-bottom: 8px;
}

.gastric-hcp.home #bs-example-navbar-collapse-1 {
    border-bottom: 0px solid #000;
    padding-bottom: 0;
}

.home div#bs-example-navbar-collapse-1::before {
    display: none;
}

.bottom-header .enhertu-nsclc-hcp-navigation li:nth-child(2) a {
    padding: 10px 0px 10px 0px;
}

.bottom-header .enhertu-nsclc-hcp-navigation li:last-child {
    margin-right: 0;
}

.indicationBox p br {
    display: none;
}

.main-content-col.pLR20 {
    padding-right: 0;
}

.gastric-hcp.home .bottom-header .enhertu-nsclc-hcp-navigation li a {
    padding: 8px 8px 8px 3px;
}

.gastric-hcp.home .bottom-header .enhertu-nsclc-hcp-navigation ul.navbar-nav>li:first-child a {
    padding-left: 0;
}

.gastric-hcp.home .bottom-header .enhertu-nsclc-hcp-navigation ul.navbar-nav>li:first-child a {
    border-bottom: 0;
}

.gastric-hcp.home .bottom-header .enhertu-nsclc-hcp-navigation ul.navbar-nav>li:first-child a span.home {
    text-align: left;
    display: block;
    position: relative;
}

.bottom-header .enhertu-nsclc-hcp-navigation li a span.home i {
    display: block;
    text-align: center;
    /* background: url(../images/mNSCLC/house-icon.png) no-repeat; */
    width: 16px;
    height: 14px;
    position: absolute;
    left: 0;
    right: 0;
    margin: auto;
    top: 3px;
}


.bottom-header .gastric-hcp.home .enhertu-nsclc-hcp-navigation li:first-child a {
    padding: 10px 0 !important;
    text-align: left;
    width: 50px;
}

.bottom-header .enhertu-nsclc-hcp-navigation.desktopViewOnly li a {
    font-size: 14px;
}

.bottom-header .enhertu-nsclc-hcp-navigation li a {
    color: #fff;
    font-size: 14px;
    line-height: 20px;
    display: block;
    text-align: center;
    font-family: "OpenSans-Bold";
    padding: 10px 5px 10px 0px;
    white-space: inherit;
    font-family: "OpenSans-Regular";
}

.bottom-header .enhertu-nsclc-hcp-navigation li a:hover {
    text-decoration: none;
}


.bottom-header .enhertu-nsclc-hcp-navigation li a span.one-word {
    width: auto;
    display: block;
}

/*.dropdown:hover .dropdown-menu {
  display: block;
}*/
.nav-tabs .dropdown-menu,
.nav-pills .dropdown-menu,
.navbar .dropdown-menu {
    margin-top: 0;
}

.dropdown-toggle::after {
    display: none;
}

.bottom-header .enhertu-nsclc-hcp-navigation li .dropdown-menu li.active {
    background-color: #ffffff !important;
}

.bottom-header .enhertu-nsclc-hcp-navigation li .dropdown-menu li:hover {
    text-decoration: none;
    background-color: #ffffff !important;
    color: #24005b;
    font-family: "OpenSans-Bold";
}

.bottom-header .enhertu-nsclc-hcp-navigation li .dropdown-menu a:hover {
    font-family: "OpenSans-Bold";
    background-color: #ffffff;
    color: #24005b;
    text-decoration: none;
}

.bottom-header .enhertu-nsclc-hcp-navigation li a.signup-link:hover {
    color: #f58025;
}

.bottom-header .enhertu-nsclc-hcp-navigation li a.dropdown-item {
    padding: 10px 10px 10px 10px;
    line-height: 15px;
    font-size: 14px;
    text-align: left;
    width: 150px;
    white-space: inherit;
    font-family: "OpenSans-Regular";
}

a.button-link.new {
    padding: 14px 1px !important;
}


.bottom-header .enhertu-nsclc-hcp-navigation li .dropdown-menu {
    position: absolute;
    top: 50px;
    left: 0;
    z-index: 1000;
    display: none;
    float: left;
    min-width: 4rem;
    padding: 0;
    margin: 0px 0 0;
    font-size: 16px;
    color: #212529;
    list-style: none;
    background-color: #fff;
    background-clip: padding-box;
    border: 0;
    border-radius: 0;
    box-shadow: 0px 4px 10px grey;
    width: 270px !important;
    text-align: left;
}

.bottom-header .enhertu-nsclc-hcp-navigation li .dropdown-menu a {
    text-align: left;
    padding: 16px 15px !important;
    white-space: normal;
    letter-spacing: .5px;
    font-size: 14px;
    text-decoration: none;
    background-color: #f8f8f9;
    color: #0e1113;
    font-family: "OpenSans-Regular";
}

.bottom-header .enhertu-nsclc-hcp-navigation li.dropdown.active {
    margin-left: 35px;
    /* text-decoration: none;
    background-color: #f8f8f9;
    color: #0e1113;
    font-family: "OpenSans-Regular"; */
}

.bottom-header .enhertu-nsclc-hcp-navigation li .dropdown-menu a.active {


    text-decoration: none;
    background-color: #ffffff !important;
    color: #24005b;
    font-family: "OpenSans-Bold";
}

.bottom-header .enhertu-nsclc-hcp-navigation li .dropdown-menu li:last-child {
    background-color: #f8f8f9;
    width: auto;
}

.bottom-header .enhertu-nsclc-hcp-navigation li a.active,
.bottom-header .enhertu-nsclc-hcp-navigation li a.tgct-enter-zip-link.clicked {
    color: #fff;
}

.bottom-header .enhertu-nsclc-hcp-navigation li a span.home i {
    display: block;
    text-align: center;
}

.bottom-header .enhertu-nsclc-hcp-navigation li a span.home i:before {
    display: none;
}

.bottom-header .enhertu-nsclc-hcp-navigation li.dropdown.active>a {
    /* border-bottom: #ea721f 10px solid;
    padding-bottom: 10px; */
}

.bottom-header .enhertu-nsclc-hcp-navigation li.dropdown>a.active,
.bottom-header .enhertu-nsclc-hcp-navigation li.dropdown.active>a {
    color: #ffffff;
    font-size: 14px;
    font-family: "OpenSans-Bold";
}

.bottom-header .enhertu-nsclc-hcp-navigation li a.active {
    /* border-bottom: #ea721f 4px solid; */
    /* padding-bottom: 16px; */
}

.bottom-header .enhertu-nsclc-hcp-navigation li a.active span {
    border-bottom: #ea721f 4px solid;
    padding-bottom: 16px;
}

.bottom-header .enhertu-nsclc-hcp-navigation li.dropdown.show a span {
    border-bottom: #ea721f 4px solid;
    padding-bottom: 16px;
}

.bottom-header .enhertu-nsclc-hcp-navigation li.show a.dropdown-toggle {
    font-family: "OpenSans-Bold";
}

.bottom-header .enhertu-nsclc-hcp-navigation li a.active span,
.bottom-header .enhertu-nsclc-hcp-navigation li a.active {
    font-family: "OpenSans-Bold";
}


.bottom-header .bottom-header-logo {
    margin-bottom: 6px;
    position: absolute;
    top: 0;
    /*background:#fff;*/
}

.gastric-hcp a.button-link {
    /* color: #fff;
    font-size: 19px;
    font-family: 'HelveticaNeueLTStd-Bd';
    background: #ea721f;
    padding: 11px 1px 7px 1px !important;
    display: block;
    text-align: center;
    position: relative;
    height: 47px;
    width: 326px;
    text-decoration: none;
    border-radius: 10px; */

    color: #fff;
    font-size: 19px;
    line-height: 19px;
    font-family: 'Helvetica75Bold';
    background: #ea721f;
    padding: 10px 9px 15px 18px !important;
    display: block;
    text-align: center;
    position: relative;
    height: auto;
    width: 338px !important;
    text-decoration: none;
    border-radius: 10px;
}

.gastric-hcp .pL0.mt-3 {
    font-size: 14px;
}

.dose-destiny-tbl .mt-4 sup {
    position: relative;
    left: -3px;
}

.gastric-hcp .clinical-trial-wrapper a.button-link {
    /* padding: 11px 0px !important; */
    padding: 8px 0px 11px 5px !important;
}

.survival-chemotherapy.ORR-chemotherapy ul li {
    list-style: none;
}

.bottom-header .bottom-header-logo img {
    margin-left: -51px;
}

.efficacy-data.medianPFS .BtmButtonDiv.row.justify-content-center .col-xl-5 a.button-link {
    width: 393px;
    margin-bottom: 25px;
}

.bottom-header .enhertu-nsclc-hcp-navigation li .dropdown-menu li.active a {
    text-decoration: none;
    background-color: #ffffff !important;
    color: #24005b;
    font-family: "OpenSans-Bold";
}

.bottom-header .enhertu-nsclc-hcp-navigation a.signup-link {
    padding: 10px;
    color: #260859;
    font-size: 14px;
    font-family: "OpenSans-Bold";
    width: 90px;
    position: relative;
    z-index: 1000;
    text-align: center;
}

.bottom-header .enhertu-nsclc-hcp-navigation a.signup-link span {
    word-break: break-all;
}

.bottom-header .enhertu-nsclc-hcp-navigation a.signup-link.active:hover,
.bottom-header .enhertu-nsclc-hcp-navigation a.signup-link.ative {
    background: transparent;
    color: #260859;
}

.bottom-header .enhertu-nsclc-hcp-navigation li .dropdown-menu.show {
    display: block !important;
}

.main-navigation .bottom-header {
    background: url(../images/mNSCLC/NavbarBg.png) no-repeat #260859;
    background-size: contain;
}

li.dropdown.cancerTypeDropdown a {
    color: #0e1113;
}

li.dropdown.cancerTypeDropdown li a {
    text-align: left !important;
    margin: 0 !important;
}

li.dropdown.cancerTypeDropdown li {
    background: #f8f8f9;
    width: 100%;
    padding: 10px 5px;
    border: #353c42 1px solid;
    border-radius: 5px;
    margin-bottom: 5px;
}

li.dropdown.cancerTypeDropdown li a span {
    font-family: "OpenSans-BoldItalic";
}

li.dropdown.cancerTypeDropdown a {
    background-image: none !important;
}

li.dropdown.cancerTypeDropdown li.active {
    background: #ffede5;
    border: #ea721f 2px solid;
    border-radius: 5px;
}

li.dropdown.cancerTypeDropdown li.active a {
    font-family: "OpenSans-Bold";
    color: #24005b;
}

li.dropdown.cancerTypeDropdown li:hover {
    background: #ffede5;
    border-radius: 5px;
}

/*----header ends------*/





/* Footer Start */
.footer {
    padding: 30px 0px;
    color: #303030;
}

.bg {
    padding: 30px 0px 40px 0px;
    color: #303030;
}

.footer p {
    font-size: 12px;
    line-height: 16px;
    margin-bottom: 0;
    color: #f6edff;
}

.footer p.F14 {
    font-size: 14px;
    line-height: 22px;
    margin-bottom: 0;
    color: #f6edff;
}

.footer-links li a {
    font-family: "OpenSans-Bold";
    color: #24005b;
    font-size: 14px;
    line-height: 26px;
}

.mobile-footer-col {
    padding: 0;
    float: left;
    width: 100%;
    background: #260859;
    /* margin-bottom: 3px; */
    border-bottom: 6px solid transparent;
    border-image-source: url(../images/mNSCLC/top-border.png);
    border-image-slice: 30;
    /* border-image-outset: 3px; */
}

.daichii-logo {
    padding: 0;
    position: relative;
}

footer.footer.bg .daiichi-logo img {
    width: 400px;
}

.contact-details {
    padding-top: 15px;
    margin-top: 0;
    color: #fff;
    width: 100%;
    float: left;
    text-align: center;
    padding-bottom: 15px;
    /* margin-bottom: 15px; */
}

ul.footer-links {
    padding: 0;
    display: flex;
    text-align: center;
    max-width: 50%;
    margin: 26px auto 38px;
    justify-content: center;
}

ul.footer-links li {
    text-align: center;
    padding: 0 25px;
    width: auto;
    float: left;
}

ul.footer-links.footerlinksBtm {
    max-width: 70%;
    margin: 0 auto;
}

ul.footer-links.footerlinksBtm li:last-child {
    text-align: center;
}

ul.footer-links.footerlinksBtm li a {
    font-family: "OpenSans-Regular";
    text-transform: inherit;
    color: #5b6670;
    text-decoration: none;
}

ul.footer-links.footerlinksBtm li a:hover {
    text-decoration: none;
}

.social,
.daichii-logo {
    max-width: 80%;
    margin: 30px auto;
    text-align: center;
}

.social img {
    padding: 0 20px;
}

.social a:hover {
    color: #0056b3;
    text-decoration: none;
}

/* Footer End */

/* ISI bar Start */
.isi-head {
    padding: 10px 0px;
    text-align: left;
    font-size: 20px;
    line-height: 24px;
    font-family: "OpenSans-Bold";
    text-transform: uppercase;
    color: #fff;
    width: 100%;
    display: block;
    padding-right: 0px;
    border-top: solid 2px #24005b;
}

.isi-head a {
    color: #24005b;
    font-size: 18px;
    line-height: 26px;
}

.isi-head a:hover {
    color: #24005b;
    text-decoration: none;
}

.isi-head span.up-arrow,
.isi-head span.down-arrow {
    background: url(../images/mNSCLC/isi-up-arrow.png) no-repeat right 8px transparent;
    /* width: 16px; */
    /* height: 11px; */
    display: inline-block;
    margin-left: 30px;
    vertical-align: middle;
    margin-top: -10px;
    position: absolute;
    right: 0px;
    top: 0px;
    bottom: 0;
    margin: auto;
    padding-right: 25px;
    z-index: 111;
    text-transform: capitalize;
}

span.rotateUp,
span.rotateDown {
    position: absolute;
    right: 0px;
    float: right;
    padding-right: 35px;
    z-index: 111;
    text-transform: capitalize;
}

.isi-head span.down-arrow {
    transform: rotate(180deg);
    -webkit-transform: rotate(180deg);
    -ms-transform: rotate(180deg);
    /* IE 9 */
    margin-right: -10px;
}

.isi-head span.down-arrow span.rotateUp {
    transform: rotate(0deg);
    -webkit-transform: rotate(0deg);
    -ms-transform: rotate(0deg);
}

.top-15-xs {
    margin-top: 25px;
}

.isi-content ul.followUp-list.pad-30 li::before {
    left: 0;
    top: 2px;
}


.warningMsgBox .followUp-list li::before {
    color: #000;
    left: 0;
    font-size: 24px;
}

#bottom {
    z-index: 2222;
    width: 100%;
    float: left;
}

#isi_new {
    background: #fff;
}

.ISI-container {
    position: relative;
    max-width: 1140px;
    margin: 0 auto;
}

.isi-content {
    font-size: 16px;
    margin-bottom: 20px;
    color: #353535;
}

.isi-head a span {
    margin-left: 0px;
}

.isi-content a,
.isi-content a:hover {
    color: #59595b;
    text-decoration: underline;
}

p.top-0-m {
    margin-bottom: 0;
}

.blackColor li {
    color: #000;
}

.warning-small-heading.no-green {
    color: #000;
}

.endpoints-tabs {
    margin-top: 15px;
}

.characteristics-table {
    margin-top: 15px;
}

.indication-info {
    margin-top: 10px;
}

.warningMsgBox p {
    margin-bottom: 5px;
    font-size: 18px;
}

.warningMsgBox {
    padding: 15px;
    border: #000 2px solid;
    margin-top: 0px;
    font-family: "OpenSans-Bold";
    color: #0e1113;
}

.warning-heading {
    width: 100%;
    font-size: 24px;
    font-family: "OpenSans-Bold";
    color: #ea721f;
    line-height: 25px;
    padding-top: 25px;
}

.F18 {
    font-size: 18px !important;
}

.warning-small-heading {
    width: 100%;
    font-size: 16px;
    color: #24005b;
    line-height: 21px;
    padding-top: 0;
    margin-bottom: 0px;
}

.underline-text {
    text-decoration: underline;
}

.isi-content.container .orange {
    color: #ee7623 !important;
    font-size: 19px;
    line-height: 21px;
}

.isi-content.container {
    max-width: 1024px;
    font-family: "Helvetica55Roman";
    margin-top: 20px;
}

.isi-content .isi-text {
    color: #353c42;
    font-size: 18px;
    margin-bottom: 20px;
    line-height: 26px;
}

.isi-content .isi-text i {
    font-family: "OpenSans-Italic";
}

ul.followUp-list.drug-int-list.Mb30.specificList li {
    color: #353c42;
}

.isi-content ul.followUp-list li {
    color: #353c42;
    margin-bottom: 10px;
}

.isi-content .warningMsgBox ul.followUp-list li {
    color: #0e1113;
}

.isi-content .warningMsgBox ul.followUp-list li:last-child {
    margin-bottom: 0px;
}

.isi-content ul.followUp-list li.middleLi:before {
    display: none
}

.isi-content .isi-text.marginBtm-0 {
    margin-bottom: 0px;
}

.isi-content ul.followUp-list.pad-30 li::before {
    left: 0;
}

p.isi-text.helveticaNeueBold.darkBlue {
    color: #000;
}

.isi-content .blacktext {
    color: #000 !important;
}

p.isi-text.helveticaNeueBold .darkBlue {
    color: #000;
}

#collapsebtn .note.text-center {
    text-align: left !important;
}

.isi-content ul.followUp-list li .helveticaNeueBold {
    color: #24005b;
}

.isi-content .followUp-list li {
    line-height: 26px;
    margin-top: 0px;
    font-size: 18px;
    position: relative;
    padding-left: 15px;
    color: #353c42;
}

.isi-content ul.followUp-list {
    padding-left: 0px;
}

.followUp-list.drug-int-list li::before {
    color: #24005b !important;
    left: 0px;
    font-size: 24px;
}

ul.followUp-list.drug-int-list.Mb30.specificList li::before {
    top: 1px;
}

.followUp-list.indication-list li ul li::before {
    content: "\2022";
}

.followUp-list.indication-list li ul {
    padding-left: 10px;
}

ul.followUp-list.indication-list {
    margin-bottom: 16px;
}

.followUp-list.indication-list li ul li {
    margin-bottom: 16px;
}

.followUp-list.indication-list li::before {
    color: #24005b !important;
    left: 0;
    top: 1px;
    font-size: 24px;
}

.followUp-list.indication-list li ul li::before {
    color: #24005b !important;
    font-size: 18px !important;
    top: 3px;
    content: "-";
    font-family: "OpenSans-Regular" !important;
}

.followUp-list.indication-list li {
    margin-bottom: 0;
    float: left;
    width: 100%;
    line-height: 26px;
    padding-left: 16px;
}

.followUp-list.indication-list li ul p {
    margin-bottom: 16px;
}

.followUp-list.indication-list li ul p:last-child {
    margin-bottom: 0;
}

.followUp-list.indication-list li span.newLine {
    float: left;
    width: 100%;
    margin-top: 16px;
}

.isi-content.container .followUp-list.drug-int-list li::before {
    top: 1px;
}

.isi-content.container .followUp-list.specificList li:before {
    top: 1px;
    color: #260859 !important;
}

.ISI-container .indicationBox {
    position: relative;
    top: -34px;
    font-size: 18px;
    color: #24005b;
    line-height: 26px;
    z-index: 1;
}

footer.footer.bg {
    background-color: #f8f8f9;
}

/*main-contentSection*/
.main-contentSection {
    float: left;
    width: 100%;
}

.main-contentSection h1 {
    font-size: 29px;
    font-family: "OpenSans-Bold";
    color: #ea721f;
    text-transform: uppercase;
}

.mainheadings h1 {
    font-size: 36px;
    line-height: 44px;
    font-family: "OpenSans-Bold";
    color: #24005b;
    text-transform: none;
    margin-bottom: 48px;
    margin-top: 48px;
}



.mainheadings span {
    font-size: 24px;
    line-height: 54px;
    font-family: "OpenSans-Bold";
    color: #24005b;
    display: block;
}

.main-contentSection h2 {
    font-size: 32px;
    line-height: 40px;
    font-family: "OpenSans-Bold";
    color: #ea721f;
}

.main-contentSection h3 {
    font-size: 24px;
    line-height: 32px;
    color: #24005b;
    font-family: 'OpenSans-Bold';
    margin: 24px 0;
}

.main-contentSection h2 span {
    font-family: "OpenSans-BoldItalic";
    font-size: 44px;
}

.homecallouts h5.card-title,
.homecallouts h2.card-title {
    color: #24005b;
    font-family: "OpenSans-Regular";
    font-size: 18px;
    line-height: 26px;
    margin-bottom: 0;
}


.homecallouts .card {
    position: relative;
    border: none;
    box-shadow: rgba(0, 0, 0, 0.35) 0px 5px 15px;
}

.homecallouts {
    /* margin: 60px 0; */
    float: left;
    width: 100%;
}

.homecallouts .card-body {
    padding: 0;
}


.homecallouts .card-footer {
    padding: 0;
    background-color: transparent;
    border-top: none;
    position: absolute;
    bottom: 0px;
}

.nccnCall img {
    width: 140px;
}

.nccnCall {
    padding-top: 64px;
}

.nccnCall.homepage {
    padding-top: 74px;
}

.nccnCall p {
    color: #24005b;
    font-size: 19px;
    font-family: "OpenSans-Bold";
    line-height: 26px;
    position: relative;
    top: -15px;
    padding-right: 0px;
}

.nccnCall p.leftBorderLine {
    border-left: #ea721f 6px solid;
    float: left;
    padding-left: 20px;
}

.nccnCall .rightBorderLine {
    border-right: #ea721f 6px solid;
    float: left;
    height: 100%;
}

.footnote.footnotespace {
    margin: 56px 0;
    border-top: 2px solid rgba(0, 0, 0, .1);
    padding: 24px 5px 0;
}

.row.footnote.footnotespace.homefootnote.margintop {
    margin-top: 40px !important
}

.footnote.footnotespace.homefootnote {
    width: 97%;
}

.footnote {
    float: left;
    width: 100%;
}

.footnote p {
    font-size: 14px;
    color: #353c42;
    line-height: 22px;
    position: relative;
    margin-bottom: 5px;
    padding-left: 0;
}

.footnote p sup {
    position: absolute;
    left: -5px;
    top: 8px;
}

.footnote p sup.last {
    position: relative;
    top: -6px;
    left: 0;
}

.footnote p .i-sup {
    left: -3px;
}

.footnote p .j-sup {
    left: -2px;
    top: 6px;
}

.footnote p .f-sup {
    left: -4px;
}

.refrencesText {
    color: #391d72;
    font-family: "OpenSans-Bold";
    font-size: 14px;
    line-height: 22px;
}

.isi-content .followUp-list.about li {
    line-height: 16px;
    margin-top: 0px;
    font-size: 12px;
    position: relative;
    padding-left: 15px;
    list-style-type: none;
    counter-increment: item;
    color: #0e1113;
    margin-bottom: 5px;
}

.followUp-list.about li::before {
    font-family: "OpenSans-Bold";
    content: counter(item) ".";
    left: -10px;
    color: #0e1113;
    top: 0;
    font-size: 12px;
    line-height: 16px;
    font-weight: 700;
}

.footer-links.footerlinkstop li a {
    position: relative;
}

.footer-links.footerlinkstop li a::after {
    position: absolute;
    content: "";
    width: 40px;
    height: 3px;
    background: #ea721f;
    left: 0;
    bottom: -10px;
}

.contact-details p a.telNum {
    color: inherit;
}

.container-820 {
    max-width: 918px;
    margin: 0 auto;
    padding: 0 15px;
}

.container-920 {
    max-width: 994px;
    margin: 0 auto;
    padding: 0 15px;
}

h1.fontsize30 {
    color: #ea721f;
    font-size: 30px;
    line-height: 1.2;
    text-align: left;
    font-family: "OpenSans-Bold";
    text-transform: none;
}

h1.fontsize32,
h2.fontsize32 {
    color: #ea721f;
    font-size: 32px;
    line-height: 1.25;
    text-align: left;
    font-family: "OpenSans-Bold";
    text-transform: none;
    margin-bottom: 0px;
}

h2.fontsize24 {
    color: #24005b;
    font-size: 24px;
    line-height: 1.33;
    text-align: left;
    font-family: "OpenSans-Bold";
}

p.fontsizeline24 {
    color: #24005b;
    font-size: 24px;
    line-height: 1.33;
    text-align: left;
    font-family: "OpenSans-Bold";
}

h3.fontsize22,
h2.fontsize22 {
    color: #24005b;
    font-size: 22px;
    line-height: 1.36;
    text-align: left;
    font-family: "OpenSans-Bold";
}

p.fontsize20 {
    color: #24005b;
    font-size: 20px;
    line-height: 1.4;
    text-align: left;
    font-family: "OpenSans-Bold";
}

p.fontsize18 {
    color: #24005b;
    font-size: 18px;
    line-height: 1.44;
    text-align: left;
    font-family: "OpenSans-Bold";
}

p.grayfontsize18 {
    color: #353c42;
    font-size: 18px;
    line-height: 26px;
    text-align: left;
    font-family: "OpenSans-Regular";
}

p.grayfontsize16 {
    color: #353c42;
    font-size: 16px;
    line-height: 1.44;
    text-align: left;
    font-family: "OpenSans-Regular";
}

p.fontsize16 {
    color: #24005b;
    font-size: 16px;
    line-height: 1.5;
    text-align: left;
    text-align: left;
    font-family: "OpenSans-Bold";
}

.nccnher2 {
    color: #24005b;
    font-size: 22px;
    line-height: 1.36;
    text-align: left;
    font-family: "OpenSans-Bold";
    padding-left: 15px;
}

a:hover {
    text-decoration: none;
}

.nccnher2 .leftBorderLine {
    border-left: #ea721f 6px solid;
    float: left;
    height: 100%;
}

.efficacy-destiny.sectionone {
    margin-bottom: 64px;
}

.efficacy-destiny.sectionone h1 {
    margin-bottom: 32px;
}

.efficacy-destiny.sectionone h2 {
    margin-bottom: 24px;
}

.fullBorderLine {
    float: left;
    width: 100%;
    background-color: #f8f8f9;
    height: 24px;
}

.fullBorderLine.heightauto {
    height: 100%;
    padding: 40px 0px;
}

.followUp-list {
    padding-left: 0px;
    font-size: 18px;
}

.followUp-list li {
    position: relative;
    padding-left: 20px;
    margin-bottom: 10px;
    color: #353c42;
}

.followUp-list li::before {
    color: #24005b;
    content: "\2022";
    font-size: 20px;
    line-height: 24px;
    font-weight: bold;
    position: absolute;
    left: 0;
    top: 2px;
    font-family: "OpenSans-Regular";
}

.efficacy-destiny.sectiontwo .followUp-list li::before {
    top: 0;
}

.efficacy-destiny.sectiontwo {
    float: left;
    width: 100%;
    padding-top: 64px;
    padding-bottom: 50px;
}

.efficacy-destiny.sectiontwo h3.fontsize22 {
    margin-bottom: 15px;
}

.efficacy-destiny.sectiontwo .onlyresults {
    margin-top: 30px;
}

.efficacy-destiny.sectiontwo .footnote.footnotespace {
    margin: 60px 0 0 0;
}

/* tableChart */
.tableChart .table-bordered td,
.tableChart .table-bordered th {
    vertical-align: middle;
    padding: 10px;
}

.tableChart .table-bordered {
    /* border-top: #ea721f 12px solid; */
    background: transparent;
    margin-bottom: 0;
}

.tableChart .table-bordered,
.table thead th {
    border-bottom: #6f5f86 1px solid;
    background: #fff;
    margin-bottom: 0;
    border-right: none;
}

.tableChart {
    float: left;
    width: 100%;
    position: relative;
}

.tableChart thead {
    background: #fffaf7;
    text-align: center;
    color: #24005b;
}

.tableChart.tableChartdestiny th {
    font-size: 18px;
    line-height: 22px;
    font-family: "OpenSans-Bold";
    padding: 20px 8px;
}

.tableChart.tableChartdestiny th.Font16 {
    font-size: 16px;
    line-height: 24px;
    font-family: "OpenSans-Bold";
    padding: 20px 8px;
}

.firstcell .followUp-list li {
    font-size: 16px;
    color: #5b6670;
    font-family: "OpenSans-Regular";
}

.tableChart.tableChartdestiny th.orangeBg {
    width: 30%;
}

.adverse-reaction .followUp-list li:last-child {
    margin-bottom: 0;
}

.adverse-reaction ul.followUp-list {
    margin-bottom: 0;
}

.tableChart.adverse-reaction td {
    padding: 20px 10px;
}

.tableChart.adverse-reaction .leftfix {
    position: relative;
    top: -15px;
}

.tableChart.tableChartdestiny.tableChart .table-bordered td {
    font-family: "OpenSans-Bold";
    color: #000;
    font-size: 16px;
    padding: 12px;
}

.tableChart.tableChartdestiny.tableChart .table-bordered td.lightbarry {
    font-family: "OpenSans-Regular";
    color: #000;
    font-size: 16px;
}

.tableChart.tableChartdestiny.tableChart .table-bordered td.lightgray {
    color: #000;
    font-family: "OpenSans-Regular";
    font-size: 16px;
    border: 1px solid #989FA6;
}

.table-bordered thead td,
.table-bordered thead th {
    border-bottom-width: 1px;
}

.table-bordered td,
.table-bordered th {
    border: 1px solid #989FA6;
}

.table thead th {
    border-bottom: 1px solid #989FA6;
}

.tableChart.tableChartdestiny.tableChart .table-bordered td.graybg {
    background-color: #f8f8f9;
    font-family: "OpenSans-Regular";
    font-size: 16px;
}

.efficacy-destiny.sectionthree {
    float: left;
    width: 100%;
    padding-top: 64px;
    padding-bottom: 0;
}

.efficacy-destiny.sectionthree h1.fontsize32 {
    margin-bottom: 15px;
}

.efficacy-destiny.sectionthree h2.fontsize24 {
    margin-bottom: 15px;
}

/* .efficacy-destiny.sectionthree .onlyresults {
    margin-top: 30px;
} */
.fullgraybg {
    float: left;
    width: 100%;
    background-color: #f8f8f9;
    padding: 50px 0;
}

.moa .fullgraybg {
    margin-top: 64px;
}

.nccnher2 p {
    margin-bottom: 0;
}

.efficacy-destiny.sectionfour .footnote.footnotespace {
    margin: 60px 0 0 0;
}

#toTopBtn img {
    width: 50px;
    z-index: 2;
    cursor: pointer;
}

#toTopBtn {
    display: none;
    position: fixed;
    bottom: 60px;
    right: 60px;
    z-index: 2222;
    padding: 10px 0px;
    width: auto;
    background: #24005b;
    border: #24005b 2px solid;
    border-radius: 5px;
}

#toTopBtn a {
    color: #fff;
    line-height: 21px;
    font-size: 18px;
    font-family: "OpenSans-SemiBold";
    padding: 10px;
}

#toTopBtn a b.fa {
    color: #fff;
    line-height: 21px;
    font-size: 22px;
    font-weight: bold;
}

h1.fontsize32 span {
    display: inherit;
    font-size: 20px;
    line-height: 1.4;
    color: #5b6670;
}

.efficacy-d {
    float: left;
    width: 100%;
    margin-bottom: 56px;
    margin-top: 56px;
    padding: 0 15px;
}

.efficacy-d.sectionone h1.fontsize32 {
    padding-bottom: 15px;
}

.efficacy-d.sectionone img {
    max-height: 400px;
}

.efficacy-d.sectionone .followUp-list {
    padding-top: 30px;
}

.efficacy-d.sectionone.above .followUp-list {
    padding-top: 10px !important;
}

.marginbottom30 {
    margin-bottom: 30px !important;
}

.efficacy-d.sectiontwo .nccnCall img {
    width: 150px;
    position: relative;
    left: -40px;
}

.efficacy-d.sectiontwo .nccnCall {
    padding-left: 15px;
}

.sitemap li a {
    text-decoration: underline;
    color: #353c42;
}

.sitemap li a:hover {
    color: #353c42;
}

p.tumor-typ {
    font-size: 16px;
    line-height: 1.5;
    text-align: left;
    color: #353c42;
    font-family: "OpenSans-Bold";
    margin-top: 40px;
}

.homecallout {
    float: left;
    width: 100%;
}

.homecallout .card-img-overlay {
    padding: 40px;
}

.homecallout .card-body {
    padding: 0;
    min-height: 111px;
}

.fullwidthbg {
    float: left;
    width: 100%;
    background: linear-gradient(to bottom, #fff 0%, #fff 10%, #ea721f1a 90%, #ea721f2b 100%);
    padding-bottom: 65px;
}

.fullgraysubhead {
    float: left;
    width: 100%;
    background-color: #f8f8f9;
    height: auto;
}

.homecallouts .card:last-child {
    margin-bottom: 0px;
}

.subheadtext {
    padding: 0;
}

.subheadtext span.rightborder {
    border-right: 1px solid #e1e3e5;
}

.subheadtext span {
    padding-right: 30px;
    font-size: 12px;
    color: #353c42;
    font-family: "OpenSans-Bold";
}

.navbar-header-three {
    position: relative;
}

#navbar-header-three {
    padding-left: 0px;
}

#navbar-header-three ul li {
    padding: 0 20px;
    line-height: normal;
}

#navbar-header-three ul li a {
    color: #353c42;
    font-size: 14px;
    line-height: 1.57;
    font-family: "OpenSans-Regular";
}

#navbar-header-three ul li a:hover {
    text-decoration: none;
    color: #353c42;
}

#navbar-header-three ul li.active a {
    border-bottom: #ee7623 4px solid;
    padding-bottom: 10px !important;
}

.fullgraysubhead .subhead-nav {
    padding: 12px 0px;
    justify-content: center;
}


.bottomborder::after {
    position: absolute;
    content: "";
    width: 40px;
    height: 3px;
    background: #ea721f;
    left: 0;
    bottom: -10px;
}

a.textlink {
    color: #24005b;
    display: block;
}

.card-link {
    margin-top: 60px;
    margin-bottom: 60px;
    text-align: center;
}

span.arrow {
    content: "";
    width: 25px;
    display: inline-block;
    background-image: url(../images/mNSCLC/download-icon.png);
    background-repeat: no-repeat;
    background-position: center right;
    margin-left: 10px;
}

a.default_btn {
    border: solid 2px #24005b;
    background-color: #fff;
    border-radius: 4px;
    padding: 16px;
    display: inline-block;
    font-family: "OpenSans-SemiBold";
    font-size: 20px;
    color: #24005b;
}


.noborderleft {
    border-left: 0px solid transparent !important;
}

.noborderright {
    border-right: 0px solid transparent !important;
}

.nobordertop {
    border-top: 2px solid #f8f8f9 !important;
}

.isi-border {
    border-top: 1px solid #e1e3e5;
}

.isi-content .isi-text.helveticaNeueBold a {
    color: #24005b;
}

.top-header {
    width: 100%;
    margin-top: 3px;
    border-top: 6px solid transparent;
    border-image-source: url(../images/mNSCLC/top-border.png);
    border-image-slice: 30;
    border-image-outset: 3px;
}

.tableChart.tableChartdestiny.adverse-reaction.tableChart .table-bordered td {
    color: #5b6670;
    font-size: 16px;
    font-family: "OpenSans-Regular";
    padding-left: 16px;
}


.btn-primary:not(:disabled):not(.disabled).active:focus,
.btn-primary:not(:disabled):not(.disabled):active:focus,
.show>.btn-primary.dropdown-toggle:focus {
    box-shadow: none;
}

.bottom-header .enhertu-nsclc-hcp-navigation li.dropdown.show a b.fa:before {
    content: "\f106";
}

.bottom-header .enhertu-nsclc-hcp-navigation li.dropdown a b.fa:before {
    content: "\f107";
}

/* header changes */
.top-header .top-header-links li:nth-child(2) a {
    margin-right: 5px;
    margin-left: 5px;
    /* width: 160px; */
}

.top-header .top-header-links li:nth-child(3) a {
    /*margin-right: 5px;
    margin-left: 5px;
     width: 127px; 
    width: 158px;*/
}

.top-header .top-header-links li:nth-child(4) a {
    /*width: 123px;*/
}

.top-header .top-header-links li:nth-child(5) a {
    /* width: 84px;*/
}

.top-header .top-header-links ul {
    float: right;
    margin-bottom: 0px;
    padding-left: 0;
}

.top-header .top-header-links li {
    float: left;
    padding: 5px 5px 5px 0px;
}

.top-header .top-header-links li.dropdown.cancerTypeDropdown {
    padding-right: 0;
    margin-right: 5px;
}

.top-header .top-header-text {
    font-size: 14px;
    padding: 0px 46px 5px 46px;
    line-height: 14px;
    color: #353c42;
    font-family: "OpenSans-Italic";
    text-align: center;
}

.desktopViewOnly li.dropdown.cancerTypeDropdown ul.dropdown-menu.show {
    margin-top: 5px;
}

.select-indicator-section {
    display: flex;
    justify-content: flex-end;
    width: 100%;
}

.grecaptcha-badge {
    bottom: 190px !important;
    z-index: 1032;
}

.top-header .top-header-links li.prescribing-info a {
    width: 158px;
}

.top-header .top-header-links li.medication-guide a {
    width: 125px;
}

.top-header .top-header-links li.patient-site a {
    width: 83px;
}

.top-header .top-header-links li.important-safety-information a {
    width: 100%;
}

.mainheadings {
    padding: 0 0;
}

.homecallouts .btn:hover {
    opacity: 0.6;
}

.row.efficacy-d.studyDesign ul.followUp-list li ul li::before {
    font-family: "OpenSans-Regular";
    color: #24005b;
    top: 2px;
    content: "–";
    font-size: 20px;
}

ul.followUp-list li ul li::before {
    position: absolute;
    content: "\f068";
    font: normal normal normal 10px/1 FontAwesome;
    color: #353c42;
    display: inline-block;
    top: 6px;
    font-size: 12px;
    left: 1px;
    font-weight: normal;
    content: "\2014";
}

.mac-os .followUp-list li::before,
.safariOnly .followUp-list li::before {
    top: 2px;
}

.mac-os .chart-efficacyTable ul.followUp-list li ul li::before {
    top: 6px;
}

.mac-os ul.followUp-list li ul li::before {
    top: 6px;
}

.mac-os ul.followUp-list li ul li,
.safariOnly ul.followUp-list li ul li {
    top: -3px;
}

.mac-os .followUp-list.about li::before,
.safariOnly .followUp-list.about li::before {
    top: 0px;
}

.noborderbtm {
    border-bottom: none !important;
}

.tableChart.tableChartdestiny th,
.tableChart.tableChartdestiny.tableChart .table-bordered td.lightgray:last-child,
.tableChart.tableChartdestiny.tableChart .table-bordered td:last-child {
    border-right: none !important;

}

.tableChart.tableChartdestiny.tableChart .table-bordered {
    border-right: none;
    border-left: none;
}

.tableChart.tableChartdestiny.tableChart .table-bordered td:first-child {
    border-left: none;
}

a.skip-main {
    background: #24005b;
    left: 0;
    outline: 0;
    padding: 10px;
    position: absolute;
    right: 0;
    text-align: center;
    top: -40px;
    z-index: 11;
    font-size: 16px;
}

a.skip-main:focus {
    color: #FFF;
    top: -1px;
}


.homecallouts .card:focus a,
.homecallouts .card:focus-visible a {
    outline: -webkit-focus-ring-color auto 1px;
}

.homecallouts .card a:focus,
.homecallouts .card a:focus-visible,
.homecallouts .card:focus-within,
.homecallouts .card:focus-visible {
    outline: -webkit-focus-ring-color auto 1px;
}

.homecallouts .card a:focus img.btn {
    display: block;
}

ul.followUp-list.safety-data.padding60 {
    margin-bottom: 20px;
}


a.nav_pink_bracket {
    background-image: linear-gradient(#FF00F5, #FF00F5), linear-gradient(#FF00F5, #FF00F5), linear-gradient(#FF00F5, #FF00F5), linear-gradient(#FF00F5, #FF00F5);
    background-repeat: no-repeat;
    background-size: 43px 3px;
    background-position: top left, top right, bottom left, bottom right;
    border: solid #FF00F5 !important;
    border-width: 0px 2px;
    padding: 10px !important;
    border-bottom: transparent !important;
    border-top: transparent !important;
    width: 96% !important;
    margin: 5px;
    display: inline-block !important;
}


.tableChart.tableChartdestiny.tableChart .table-bordered th,
.tableChart.tableChartdestiny.tableChart .table-bordered td {
    border: #6f5f86 1px solid;
}


#onetrust-consent-sdk #onetrust-pc-btn-handler {
    margin-top: 1rem;
    width: 209px !important;
}

#onetrust-banner-sdk #onetrust-policy {
    margin-right: 10px;
}

#onetrust-consent-sdk #onetrust-accept-btn-handler {
    width: 209px !important;
}


.table-bordered .graybg-color {
    background-color: #e1e3e5 !important;
}

.table-bordered .lightPink-color {
    background-color: #ffede5 !important;
}

.w-20 {
    width: 20%;
}

.tableChart.tableChartdestiny.tableChart .table-bordered th.break-text br {
    display: none;
}

ul.followUp-list.safety-data.padding64 {
    margin-bottom: 22px;
}

.table-bordered .graybgg-color {
    background-color: #e5e3eb !important;
}

.card.call-body {
    position: relative;
    float: left;
    width: 100%;

}

.pink_bracket {
    color: #fa00ff;
    background-image: linear-gradient(#fa00ff, #fa00ff), linear-gradient(#fa00ff, #fa00ff), linear-gradient(#fa00ff, #fa00ff), linear-gradient(#fa00ff, #fa00ff) !important;
    background-repeat: no-repeat;
    background-size: 10px 3px;
    background-position: top left, top right, bottom left, bottom right;
    border: solid #fa00ff !important;
    border-width: 0 2px;
    padding: 10px 10px 10px 10px;
    border-bottom: transparent !important;
    border-top: transparent !important;
    width: 100%;
    margin-bottom: 10px !important;
    display: block;
}

.blackColor {
    color: #000 !important;
}

.landingPageHcp {
    float: left;
    width: 100%;
    height: auto;
    background: url(../images/mNSCLC/home/curve-banner-img-desk.png) no-repeat;
    background-position: top left;
    background-size: 100% 100%;
    padding: 40px 0 0;
}

.landingPageHcp .leftDiv {
    position: relative;
}

#trialDesigns {
    /* margin: 40px 0 56px; */
}

.landingPageHcp h1.headingmain {
    color: #24005b;
    font-size: 36px;
    font-family: 'OpenSans-Bold';
    text-transform: none;
    position: absolute;
    top: 50%;
    transform: translateY(-50%);
    margin-bottom: 0px;
}

.main-contentSection.home-section .homecallouts .card-body {
    padding: 0;
    min-height: auto;
    position: relative;
}

.homecallouts .card-link-sectionTwo p.card-text {
    min-height: 79px;
}

.homecallouts p.card-text {
    color: #24005b;
    font-family: 'OpenSans-SemiBold';
    font-size: 20px;
    line-height: 24px;
    position: relative;
    margin-bottom: 0;
}

.card-text-span {
    font-family: "OpenSans-Regular";
    font-size: 17px;
    line-height: 26px;
    color: #24005b;
}

.homecallouts .card-footer {
    padding: 0;
    background-color: transparent;
    border-top: none;
    position: absolute;
    top: 50%;
    right: 15px;
    transform: translateY(-50%);
    bottom: auto;
}

.homecallouts .btn {
    margin: 0px 0;
    padding: 0;
}

.homecallouts .card-img-overlay {
    padding: 24px 12px;
    height: auto;
}

.homecallouts .card {
    position: relative;
    border: none;
    box-shadow: rgba(0, 0, 0, 0.35) 0px 5px 15px;
    background: #fff;
    width: 383px;
    height: 104px;
    border-bottom: #ea721f 8px solid;
    border-radius: 0px;
    margin-bottom: 16px;
}

.secondSection h2 {
    color: #24005b;
    font-size: 24px !important;
    font-family: "OpenSans-Bold";
    margin-bottom: 16px;
}

.secondSection p,
.secondSection ul li {
    color: #353c42;
    font-size: 18px;
    line-height: 26px;
    margin-bottom: 16px;
}

.studyDesign {
    margin: 56px 0 24px;
}

.studyDesign h2 {
    color: #24005b;
    font-size: 24px !important;
    font-family: "OpenSans-Bold";
    margin-bottom: 16px;
    line-height: 32px;
}

.studyDesign p,
.studyDesign ul li {
    color: #353c42;
    font-size: 18px;
    line-height: 26px;
    margin-bottom: 16px;
}
.row.efficacy-d.studyDesign ul.followUp-list.safety-data {
    margin-bottom: 0;
}

.studyDesign .newH2 {
    margin-top: 8px;
}

.nccnDiv.card .card-img-overlay {
    padding: 24px;
    text-align: center;
}

.nccnDiv.card .card-img-overlay img {
    width: 164px;
    height: 109px;
    margin: 48px auto 0;
}

.nccnBtm {
    border-top: #ea721f 6px solid;
    padding-top: 32px;
    margin-top: 24px;
    float: left;
    width: 100%;
}

.nccnBtm p span {
    color: #24005b;
    font-size: 18px;
    line-height: 26px;
    font-family: "OpenSans-Bold";
    float: left;
    width: 100%;
    text-align: left;
}

.nccnBtm p {
    color: #24005b;
    font-size: 18px;
    line-height: 26px;
    float: left;
    width: 100%;
    text-align: left;
    margin-bottom: 0px;
}

.nccnDiv {
    margin-right: 1%;
    min-height: 449px;
    max-width: 49%;
    border-radius: 0px;
    border-bottom: #ea721f 6px solid;
}

.nccnDiv.rightNccn {
    margin-right: 0px;
    margin-left: 1%;
}

.nccnDiv .nccnImage {

    text-align: center;
}

.nccnDiv .nccnImage img {
    width: 164px;
    height: 109px;
}

.container-790 {
    max-width: 790px;
    margin: 0 auto;
}

div#nccnGuidelines {
    padding: 0 15px;
}

.nccnBox {
    margin-top: 24px;
    padding: 0 15px;
}

.textCallout {
    border-left: #ea721f 6px solid;
    padding-left: 24px;
    margin: 0 15px;
}

.textCallout h2 {
    color: #24005b;
    font-size: 32px;
    line-height: 40px;
    font-family: "OpenSans-Bold";
}

.textCallout p {
    color: #24005b;
    font-size: 20px;
    line-height: 28px;
}

.her2PAtient h3 {
    font-size: 24px;
    line-height: 32px;
    color: #24005b;
    font-family: 'OpenSans-Bold';
    margin: 24px 0;
    float: left;
    width: 100%;
}

.her2PAtient {
    margin: 56px 0 0 0;
    float: left;
    width: 100%;
}

.her2PAtient .row.col-xl-12,
.efficacy-d.sectiontwo.tableSection.ngsSection .row.col-xl-12 {
    margin: 0;
    padding: 0;
}

.her2PAtient .greyBox {
    background: #e5e3eb;
    padding: 16px 24px 16px 50px;
    border-left: #24005b 6px solid;
    max-width: 368px;
    margin-right: 24px;
}

.her2PAtient .pinkBox {
    background: #ffede5;
    padding: 16px 24px 16px 39px;
    border-left: #ea721f 6px solid;
    max-width: 368px;
}

.her2PAtient .greyBox p {
    color: #24005b;
    font-size: 18px;
    font-family: 'OpenSans-Bold';
    line-height: 26px;
}

.her2PAtient .greyBox span.numbers {
    color: #24005b;
    font-size: 56px;
    font-family: 'OpenSans-Bold';
    line-height: 52px;
}

.her2PAtient .pinkBox p {
    color: #24005b;
    font-size: 18px;
    font-family: 'OpenSans-Bold';
    line-height: 26px;
}

.her2PAtient .pinkBox span.numbers {
    color: #24005b;
    font-size: 56px;
    font-family: 'OpenSans-Bold';
    line-height: 52px;
}

.solidTumorText p {
    margin: 0px 0 48px;
    float: left;
    width: 100%;
}

#her2Testing .card .card-img-overlay img {
    width: 134px;
    height: 106px;
}

#her2Testing .card {
    position: relative;
    border: none;
    box-shadow: rgba(0, 0, 0, 0.35) 0px 5px 15px;
    padding: 0;
    border-radius: 0px;
    border-bottom: #ea721f 6px solid;
}

.tableChart.tableChartdestiny.tableChart .table-bordered th.noBg {
    background: #fff;
    width: 33.3%;
}

.tableChart.tableChartdestiny.tableChart .table-bordered th.greyBg {
    background: #e5e3eb;
    width: 33.3%;
}

.tableChart.tableChartdestiny.tableChart .table-bordered th.pinkBg {
    background: #ffede5;
    width: 33.3%;
}

.greText {
    font-size: 16px;
    color: #000;
    line-height: 24px;
}

.tableSection h2 {
    margin-bottom: 32px;

}

.nccnDiv {
    max-width: 49%;
    min-height: 100%;
}

.footnote.footnotespace p:last-child {
    margin-bottom: 0px;
}

.boxlayout,
.nccnDiv,
.mutationNsclcCard {
    position: relative;
    box-shadow: rgba(0, 0, 0, 0.35) 0px 5px 15px;
    padding: 48px 24px;
    border-bottom: #ea721f 6px solid;
    background: transparent;
    margin-bottom: 0px;
    width: 100%;
}

.boxlayout .topright,
.nccnDiv .topright,
.mutationNsclcCard .topright {
    position: absolute;
    top: 0;
    right: 0;
    width: 200px;
    z-index: -1;
}

.boxlayout p.topHeading {
    color: #24005b;
    font-size: 24px;
    font-family: 'OpenSans-Bold';
    line-height: 32px;
}

.BOXED {
    color: #353c42;
    font-size: 18px;
    line-height: inherit;
    font-family: 'OpenSans-BoldItalic';
    font-weight: 700;
    border: #24005b 2px solid;
    width: max-content;
    padding: 8px;
    border-radius: 6px;
    margin-bottom: 16px;
}

.orangeBox {
    border: #ea721f 2px solid;
    font-family: 'OpenSans-Bold';
}

.boxDiv {
    display: flex;
}

.boxDiv .BOXED.orangeBox {
    margin-left: 8px;
}

.Font22 p {
    font-size: 22px;
}

.refrencesTexClin.Cancer.Rest {
    color: #24005b;
    font-size: 14px;
    line-height: 22px;
    font-family: 'OpenSans-Bold';
    margin-bottom: 8px;
}

ul.followUp-list.about.refrence {
    padding-left: 10px;
}

.top-header .top-header-links li.dropdown.cancerTypeDropdown a::after {
    background: none;
}

.mutationNsclc .card-img-overlay {
    padding: 48px 24px;
}

.mutationNsclc .card-img-overlay .card-body {
    padding: 0px;
}

.Nsclcoverlay img {
    width: 134px;
}

.Nsclcoverlay {
    margin-top: 16px;
    min-height: 78px;
}

.mutationNsclcCard {
    margin-bottom: 0px;
}

.ngsSection h2,
#her2Testing h2 {
    margin-bottom: 0px;
}

.efficacy-d.sectiontwo.tableSection.ngsSection .boxlayout {
    margin-bottom: 24px;
}

.wordWrap {
    white-space: nowrap;
}

.underline-text {
    text-decoration: underline;
    text-decoration-line: underline;
    text-decoration-style: solid;
    text-decoration-skip-ink: none;
    text-decoration-thickness: auto;
    text-underline-offset: auto;
    text-underline-position: from-font;
}

ul.followUp-list.pad-30.bold-text.blackColor {
    margin-bottom: 0px;
}

span.urlLinkBreak {
    word-break: break-all;
}

/* homeBannerMain Start */

.homeBannerMain {
    position: relative;
    background: #28015d;
}

.homeBannerBgMain {
    position: relative;
    width: 100%;
    max-width: 1440px;
    margin: 0 auto;
    height: 956px;
    overflow: hidden;
}

video#myVideoBanner {
    display: block;
    -webkit-box-sizing: border-box;
    box-sizing: border-box;
    width: 100%;
    overflow: hidden;
    object-fit: cover;
    object-position: top;
    height: 956px;
}

.homeBannerBody {
    position: absolute;
    /* top: 22%; */
    left: 0;
    right: 0;
    top: 50%;
    transform: translateY(-50%);
}

.homeBannerContainer1040 {
    position: relative;
    width: 100%;
    margin-left: auto;
    margin-right: auto;
    padding: 0 32px;
    max-width: 1088px;
}

.homeBannerContent {
    position: relative;
}

.homeBreastlink .indicationLink {
    display: inline-block;
    margin-bottom: 16px;
}

.homeBreastlink .indicationLink img {
    /* width: 144px; */
    height: 64px;
    object-fit: contain;
}

h1.her2NSCLCHead {
    font-family: "OpenSans-Bold";
    font-size: 36px;
    line-height: 1.22;
    text-align: left;
    color: #fff;
    margin-top: 0;
    margin-bottom: 32px;
    width: 84%;
    text-transform: none;
}

h1.her2Head {
    font-family: "OpenSans-Bold";
    font-size: 50px;
    line-height: 1.28;
    text-align: left;
    color: #fff;
    margin-top: 5px;
    margin-bottom: 24px;
    width: 100%;
    text-transform: none;
}

p.topSubHead {
    font-family: "OpenSans-Bold";
    font-size: 16px;
    line-height: 1.5;
    text-align: left;
    color: #fff;
    margin-bottom: 8px;
}

.homeBreastlink {
    padding-top: 0;
}

.homeBannerBottonMain {
    display: flex;
    width: 100%;
    gap: 20px;
}

.bannerButtonLeft {
    width: 50%;
}

.bannerCommonButton {
    position: relative;
}

.bannerCommonButton a {
    box-sizing: border-box;
    text-align: left;
    position: relative;
    padding: 24px 24px;
    width: 100%;
    display: flex;
    align-items: center;
    text-decoration: none;
}

.btnTextMain span {
    display: block;
}

/* pseudo-element for the border */
.bannerCommonButton a::before {
    content: "";
    position: absolute;
    inset: 0;
    /* fills the whole element */
    border: 2px solid #f89335;
    pointer-events: none;
    transition: border-width 0.2s ease, border-color 0.2s ease;
}

/* hover effect */
.bannerCommonButton:hover a::before {
    border-width: 4px;
    /* grows inward */
    border-color: #ffb68b;
}

.bannerCommonButton::before {
    content: "";
    position: absolute;
    right: 20px;
    top: 50%;
    transform: translateY(-50%);
    width: 20px;
    height: 22px;
    background: url(../images/home/rightarrow.svg) no-repeat center center;
    background-size: contain;
}

.bannerCommonButton a span.btnText {
    font-family: "OpenSans-Bold";
    font-size: 24px;
    line-height: 1.33;
    text-align: left;
    color: #fff;
    width: 410px;
}

.bannerCommonButton a span.btnTopText {
    font-family: "OpenSans-Regular";
    font-size: 18px;
    line-height: 1.53;
    text-align: left;
    color: #fff;
}

.bannerButtonMiddle {
    width: 50%;
}

.bannerButtonRight {
    width: 50%;
}

.bannerCommonButton:hover::before {
    background: url("../images/home/rightarrow-hover.svg") no-repeat center center;
    background-size: contain;
}

.bannerCommonButton p.indicationNew {
    color: #F89335;
    font-size: 20px;
    font-family: 'OpenSans-Bold';
    margin-bottom: 8px;
    border-bottom: 2px solid #baa8ff;
    display: inline-block;
    padding-bottom: 5px;
    line-height: normal;
}

.bannerCommonButton p.indicationNew.pink {
    color: #f0f;
}

.bannerCommonButton p.bannerHead {
    font-family: "OpenSans-Bold";
    font-size: 20px;
    line-height: normal;
    text-align: left;
    color: #fff;
    margin-bottom: 0;
}

.bannerCommonButton ul.banner-list {
    padding-left: 0;
    margin-bottom: 0;
    width: 100%;
    max-width: 440px;
}

.bannerCommonButton ul.banner-list li {
    font-family: "OpenSans-Regular";
    font-size: 14px;
    line-height: 1.57;
    text-align: left;
    color: #fff;
    position: relative;
    padding-left: 6px;
}

ul.banner-list li::before {
    color: #fff;
    content: "\2022";
    position: absolute;
    left: 0px;
    top: 0;
}

h1.her2Head br {
    display: none;
}

p.bannerHead br {
    display: none;
}

.homeBannerBottonMain.topBannerBtn {
    padding-bottom: 20px;
}

.mobileViewOnlyIndication {
    display: none;
}

p.bannerHeadText {
    font-family: "OpenSans-Bold";
    font-size: 20px;
    line-height: normal;
    text-align: left;
    color: #fff;
    margin-bottom: 0;
}

.bannerList li {
    color: #fff;
    font-size: 14px;
    line-height: 1.57;
    margin-bottom: 0;
    padding-left: 8px;
}

.bannerList ul.followUp-list {
    margin-bottom: 0;
}

.bannerList .followUp-list li::before {
    color: #fff;
    margin-bottom: 0;
}

.bannerList ul.followUp-list li:last-child {
    margin-bottom: 0;
}

.bannerList {
    max-width: 450px;
}

.indicationsBannerSection {
    position: relative;
    width: 100%;
    margin-top: 40px;
}

.main-contentSection .indicationsBannerSection h2 {
    font-family: "OpenSans-Bold";
    font-size: 24px;
    line-height: 1.33;
    text-align: left;
    color: #fff;
    margin-bottom: 16px;
}

.indicationsBannerSection p {
    font-family: "OpenSans-Regular";
    font-size: 18px;
    line-height: 1.44;
    text-align: left;
    color: #fff;
}

.indicationsBannerSection .followUp-list {}

.indicationsBannerSection .followUp-list ul {
    margin-bottom: 0;
}

.indicationsBannerSection ul.followUp-list li {
    font-family: "OpenSans-Regular";
    font-size: 18px;
    line-height: 1.44;
    text-align: left;
    color: #fff;
    margin-bottom: 16px;
}

.indicationsBannerSection .followUp-list li::before {
    color: #fff;
    content: "\2022";
    font-size: 20px;
    line-height: 24px;
    font-weight: bold;
    position: absolute;
    left: 0;
    top: 2px;
    font-family: "OpenSans-Regular";
}

.btnTextMain i {
    font-family: "OpenSans-BoldItalic" !important;
}

.btnTextMain {
    display: flex;
    align-items: center;
    min-height: 100px;
}

h2.h2FontBlack {
    color: #8c295a;
}

p.blackfontSize20 {
    font-family: "OpenSans-Bold";
    font-size: 20px;
    line-height: 1.4;
    text-align: left;
    color: #353c42;
    margin-top: 24px;
    margin-bottom: 24px;
}

h3.littleFont {
    margin-top: 24px;
    float: left;
    margin-bottom: 0;
}

p.fontsize18.obtainText {
    margin-bottom: 16px;
}

p.fontsize18.IHCText {
    color: #353c42;
    margin-bottom: 0;
}

ul.followUp-list.safety-data.newlyFollow {
    margin-bottom: 24px;
}

ul.followUp-list.safety-data.newlyFollow li:last-child {
    margin-bottom: 0;
}
ul.followUp-list.about.refrence a {
    color: #0e1113;
    text-decoration: none;
}
ul.followUp-list.about.refrence a:hover {
    color: #0e1113 !important;
    text-decoration: none !important;
}